Early Second Trimester Asymmetric Growth and Mosaic Triploid Liveborn

Oligohydramnios during the Early Second Trimester

Oligohydramnios developing early in pregnancy is less common, and the fetal outcomes are usually poor. This is because prolonged decrease in amniotic fluid may cause compression sequences, such as pulmonary hypoplasia, muscle hypotrophy or joint constriction. Early-onset oligohydramnios may be caused by preterm premature rupture of membranes (pPROM) or decreased secretion of amniotic fluid. Ear...

Simultaneous formation of haploid, diploid and triploid eggs in diploid-triploid mosaic loaches

IVF culture medium affects human intrauterine growth as early as the second trimester of pregnancy.

STUDY QUESTION When does a difference in human intrauterine growth of singletons conceived after IVF and embryo culture in two different culture media appear? SUMMARY ANSWER Differences in fetal development after culture of embryos in one of two IVF media were apparent as early as the second trimester of pregnancy. WHAT IS KNOWN ALREADY Abnormal fetal growth patterns are a major risk factor...

Early Second-Trimester Serum MiRNA Profiling Predicts Gestational Diabetes Mellitus

BACKGROUND Gestational diabetes mellitus (GDM) is one type of diabetes that presents during pregnancy and significantly increases the risk of a number of adverse consequences for the fetus and mother. The microRNAs (miRNA) have recently been demonstrated to abundantly and stably exist in serum and to be potentially disease-specific. However, no reported study investigates the associations betwe...

Hepatocyte growth factor concentration in the early second-trimester amniotic fluid does not predict fetal growth at birth.

The purpose of this study was to evaluate whether hepatocyte growth factor (HGF) concentrations in the early second-trimester amniotic fluid predict fetal growth at birth. HGF and insulin-like growth factor-I (IGF-I) concentrations in the early second-trimester amniotic fluid were measured in 12 pregnancies with small for gestational age (SGA) infants, 84 pregnancies with appropriate for gestat...